Viagra (sildenafil) is a phosphodiesterase-5 (PDE5) inhibitor used for the treatment of ED Side effects of Generic Sildenafil Citrate or Suhagra include:

  • back pain;
  • stuffy nose;
  • and dizziness;
  • warmth or redness in the face, neck, or chest;
  • upset stomach;
  • headaches;
  • ringing in the ears;
  • an inability to differentiate between the colors green and blue;
  • loss of hearing;
  • diarrhea;
  • stomach pain;
  • nausea;
  • memory problems.
See Contraindications. Potentiates hypotensive and sedative effects of tizanidine. Avoid theophylline (increases theophylline levels), duloxetine, zolpidem; oral forms with antacids, multivalent cations, calcium, iron, zinc, sucralfate, buffered forms of didanosine, other highly buffered drugs (may give ciprofloxacin 2hrs before or 6hrs after); high ciprofloxacin doses with NSAIDs (increases seizure risk). Potentiates caffeine/xanthine derivatives. Potentiated by probenecid. Severe hypoglycemia with oral antidiabetics (eg, glyburide, glimepiride). Increased serum creatinine with cyclosporine. Monitor methotrexate, oral anticoagulants (potentiation), phenytoin (variable effects), clozapine and ropinirole (potentiation). Increased risk of tendinitis/tendon rupture with corticosteroids. Caution with Viagra, other drugs that lower seizure threshold. Increased risk of QT prolongation with Class IA or III antiarrhythmics, TCAs, macrolides, antipsychotics. Reduced absorption with omeprazole (XR).

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Data from 3 large, well-controlled efficacy trials demonstrate that treatment with Generic Avodart 0.5mg (0.5 mg once daily) reduces the risk of both AUR and BPH-related surgical intervention relative to placebo, improves BPH-related symptoms, decreases prostate volume, and increases maximum urinary flow rates. These data suggest that Avodart 0.5 mg arrests the disease process of BPH in men with an enlarged prostate.
Vardenafil's indications and contraindications are the same as with other PDE inhibitors; it is closely related in function to generic Viagra (Viagra) and Generic Cialis (Cialis). The difference between the Vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.

Hepatic Impairment

Other Concomitant Therapy: Although specific interaction trials were not performed with other compounds, approximately 90% of the subjects in the 3 randomized, double-blind, placebo-controlled safety and efficacy trials receiving Avodart 0.5 mg were taking other drugs concomitantly. No clinically significant adverse interactions could be attributed to the combination of Avodart and concurrent therapy when Avodart was coadministered with anti-hyperlipidemics, angiotensin-converting enzyme (ACE) inhibitors, beta-adrenergic blocking agents, calcium channel blockers, corticosteroids, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), phosphodiesterase Type V inhibitors, and quinolone antibiotics.
Report this month that Sildenafil Citrate increases the amount of oxytocin released by stimulation of the posterior pituitary gland, a small structure directly underneath the brain that regulates hormone levels in response to neural signals.